When I was in paramedic school, I performed my internship at one of the largest urban centers in the country. At that time, the city was in the middle of a heroin crisis. EMS units were responding to numerous overdose calls daily, including mine.
We ran the overdose calls in a fairly routine way: bag the patient, start an IV and administer a coma cocktail of naloxone, thiamine and dextrose. All was well and good, except when the patient regained consciousness and refused to be transported.